Wednesday, December 16, 2015

Nimesulide tablet dose


The main purpose of Nimesulide tablets is for the treatment of painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.
Oral dosage form prescribed for the shortest duration
Nimesulide is indicated for the treatment of acute pain, Painful osteoarthritis (Swelling in the joints) and primary dysmenorrhoea.

It is considered as the most prescribed tablet for variety of painful inflammatory conditions including those associated with osteoarthritis, postoperative trauma, sports injuries.
 Nimesulide medication is a non-steroidal anti-inflammatory drug, prescribed for painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.
In adults:100 mg In children: 5 mg/kg/day in 2 or 3 divided doses.
Nimesulide has superior gastrointestinal safety as compared to other NSAIDs. Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.
Adults:
100mg bid after meal.
Elderly:
In elderly patients there is no need to reduce the daily dosage
Children (< 12 years):
Nimesulide 100mg Tablets/granules is contraindicated in these patients.
Adolescents (from 12 to 18 years):

Sunday, December 6, 2015

Nimesulide Tablet Structure

Nimesulide Tablet Structure


Nimesulide is generally utilized as a part of the treatment of inflammatory torment which hinders the protein cyclooxygenase-2 (COX-2) and has better gastro-intestinal mediocrity in addition to different NSAIDs in its class.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatory drug.

It is available in more than 50 countries worldwide.



Features: 
  • Amongst most effective yet gastro friendly 
  • Non steroidal anti inflammatory drug (NSAID) 
  • Nimesulide targets COX-2 an enzyme responsible for inflammation & pain. 
Uses of Nimesulide:
  • Nimesulide tablet has excellent gastrointestinal safety in comparison to other medication. 
  • Rapid onset of action within 15 minutes 
  • Rapidly relieves pain in arthritis

    Nimesulide Gel Uses

    Nimesulide Gel Uses

    Nimesulide is available in various forms including tablets, suppositories, water-soluble powders, and topical gels.

    Original Nimesulide is commercially available as tablets (100 mg), granules for oral suspension (100 mg), suppositories (200 mg) and gel (3%).

    Nimesulide Gel (Nimesulide/Methyl Salicylate/Menthol/Capsaicin) is used to treat chronic and acute musculoskeletal disorders such as soft tissue injuries or non-articular rheumatic disorders, including discomfort in the muscles, tendonitis, back pain/ache, arthritis, tenosynovitis sprains, or strains.

    Dosage and Administration

    Nimesulide Gel is apply to the affected area, rubbing in a thin layer of the gel 2 to 4 times every day. For best results, wash the application area beforehand to clean away any oil, grease, or bacteria, allowing the gel to absorb more easily.

    Nimesulide is available in assortment of structures like as tablets and syrup for oral organization and gels for topical application.

    The anti-inflammatory activity of topically applied Nimesulide gel demonstrations particularly on cyclo-oxygenase-2 which applies less gastrointestinal antagonistic impacts than different NSAIDs.

    Nimesulide Tablet Dose

    Nimesulide Tablet Dose

    Nimesulide medication is a non-steroidal anti-inflammatory drug, prescribed for painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

    Nimesulide Dosage:

    Adults:
     100 mg twice daily
    Children: 5mg/kg of body weight in 2 or 3 divided doses.

    The minimum effective dose should be used for the shortest duration to reduce the undesirable effects.

    The maximum duration of a treatment course with Nimesulide is 15 days.

    Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required by the clinical situation.

    Adults:
    100mg bid after meal.

    Elderly:
    In elderly patients there is no need to reduce the daily dosage
    Oral
    Dysmenorrhoea
    Adult: 100 mg bid.

    Oral
    Osteoarthritis

    Adult: 100 mg bid

    Oral
    Postoperative pain

    Adult: 100 mg bid. 

    Oral
    Acute pain

    Adult: 100 mg bid.

    Rectal
    Acute pain

    Adult: 200 mg bid

    Rectal
    Osteoarthritis

    Adult: 200 mg bid

    Rectal
    Primary dysmenorrhoea

    Adult: 200 mg bid

    Nimesulide Tablet Efficacy

    The abilities of NSAID’s drug nimesulide to inhibit COX-2 preferentially and to exert other novel anti-inflammatory actions are consistent with good efficacy and safety with highly effective in reducing pain, inflammation and also helps in better penetration of the antibiotics.

    Nimesulide posses analgesic properties with multifactorial mode of action for the treatment of musculoskeletal system, dysmenorrhoea, and acute pain.

    It also undergoes extensive biotransformation. The recent study on the basis of analgesic activity of Nimesulide has proved that it has a quicker onset which shows relief from pain relief and inflammation within 15 minutes from drug intake.

    Nimesulide is recommended for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea.

    Nimesulide Tablet Indications

    Nimesulide Tablet Indication

    Anti-inflammatory Analgesics tablet – Nimesulide is required for the quick treatment of severe muscular pains and inflammatory problems. Nimesulide tablets is available in different countries in the world.

    Nimesulide is Indicated in reducing pain, fever and inflammatory symptoms of:
    • Chronic arthritis
    • Osteo arthritis
    • Otorhinolary diseases
    • Soft tissues and oral cavity inflammation
    • Dysmenorrhoea
    • Thrombosis
    • Urogenital disease
    • Postoperative pain states
    • Sports injuries
    Uses of Nimesulide:
    • Rapid onset of action within 15 minutes
    • Rapidly relieves pain in arthritis

    Nimesulide Medicine

    Nimesulide Medicine

    Nimesulide 100mg Therapeutic indications:
    • Treatment of acute pain
    • Symptomatic treatment of painful osteoarthritis
    • Primary dysmenorrhoea.

    Nimesulide Medicine uses:
    • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
    • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
    • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
    • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.
    • Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities

    Nimesulide medicines are recommended for short duration of 15 days.